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One way that you can smooth out your fabric when using fusible fleece is to first fuse a layer of Shape Flex to the fabric, then follow it with a layer of fusible fleece.

Pellon SF-101 Shape Flex Fusible Woven

I use this in 100% of my bags. I might use it in different ways, but bar none, it is the most important interfacing in my stash. I fuse Shape Flex to every single pocket that I make. I fuse it to facings in garments. I for sure fuse it to an area around a zipper to help reinforce that area.

What Sara has to add -
Shape Flex will make a quilt-weight cotton have the feel, once fused, of a decor-weight or canvas-weight fabric.
It will give the fabric a bit of sturdiness.
As with the previous interfacings, the rough tacky side should go against the wrong side of your fabric before ironing.
It is perfect as a stand-alone interfacing if you are making a small pouch or other smaller accessory.
You can even combine it with other interfacings.
Someone asked me the other day what is the most interfacing I have used on one piece of fabric, and the answer is 3.
I like to experiment a lot, and there is no right or wrong answer. I might use a layer of Shape Flex, one of Thermolam, and another of 520.
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Shape-Flex Fusible Interfacing  from Pellon Black Shape-Flex Fusible Interfacing BLACK SF101B 20" x2 yards Pellon
Price: C$17.99
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PPSF101-60 Pellon Shape-Flex White, 60" x 1yd Shape-Flex Fusible Interfacing PPSF101 White, 60" x 1 yd Pellon
Price: C$21.99
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SF101 Shape Flex from Pellon White, 20" x 10yd bolt Shape-Flex Fusible Interfacing SF101 20" x 10yd bolt Pellon
Price: C$99.99
Special Price! C$81.99
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Shape Flex from Pellon  SF101  White, 20" x 25yds Bolt Shape-Flex Fusible interfacing SF101 White 20" x 25yds Wholesale
Price: C$259.99
Special Price! C$153.99
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SF101 Pellon Shape-Flex White, 20" x 2yd Shape-Flex Fusible Interfacing SF101 White, 20" x 2yd Pellon
Price: C$17.99
You save C$3.00!